I have been facing this issue lately with Brave browser and after some digging, I learned that it has something to do with GPUs. Disabling ‘Use hardware acceleration when available’ option resolved the issue for me.
Adding Global Keyboard Shortcuts to your macOS app can be a pain as there isn’t a Cocoa API for the same. You would have to rely on the old, most of which are deprecated, Carbon API.
For me personally, it is a mixed feeling working from home. On one hand, I have the flexibility with when to work and when not to but on the other hand, it is sometimes hard for me to find that fine line between work and life. There are days when I keep working even after office hours without realizing that I have got my life wife too :)